Trimethylamine N-oxide dihydrate

Trimethylamine N-oxide dihydrate
  • CAS No.:62637-93-8
  • Grade:99.86%
  • Formula:C3H13NO3
  • M.W.:111.14
  • Solvent:≥ 2.5 mg/mL (22.49 mM); Clear solution

Overview

Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide dihydrate induces inflammation by activating the ROS/NLRP3 inflammasome . Trimethylamine N-oxide dihydrate also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > TGF-beta/Smad

Product Information

  • Catalog No.: HY-108915
  • CAS No.: 62637-93-8
  • Molecular Formula: C3H13NO3
  • Molecular Weight: 111.14
  • Purity: 99.86%
  • Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
  • Solubility: ≥ 2.5 mg/mL (22.49 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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