Trazium esilate (EGYT-3615) is an antidepressant, which influences the central dopaminergic system. Trazium esilate synergizes amphetamine, potentiates stereotypy and hypermotility. Trazium esilate blocks Apomorphine ( HY-12723 )-induced hypothermic and the stereotypy, and Bulbocapnine ( HY-W436270 )-induced cataleptic state. Trazium esilate enhances the effect of Norepinephrine ( HY-13715 ) on isolated vas deferens of the rat.
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