(S)-Padsevonil

Overview

(S)-Padsevonil is the S-enantiomer of Padsevonil ( HY-109009 ).Padsevonil (UCB0942) is a potent antiepileptic agent that selectively acts on presynaptic and postsynaptic targets. Padsevonil binds to synaptic vesicular protein 2 ( SV2 ) with high affinity. Padsevonil is also a positive allosteric modulator and partial agonist of GABA A R , with high potency against α1 and α5 receptors. Padsevonil has antiepileptic effects in a variety of rodent models.

Application

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Product Information

• Catalog No.: HY-109009A
• CAS No.: 1294001-37-8
• Molecular Formula: C14H14ClF5N4O2S
• Molecular Weight: 432.80
• Purity: 99.40%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.55 mM); Clear solution
• Availability: In-stock

Source

Original product source