Firibastat

Overview

Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor ( K i =200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats.

Application

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Product Information

• Catalog No.: HY-109058
• CAS No.: 648927-86-0
• Molecular Formula: C8H20N2O6S4
• Molecular Weight: 368.51
• Purity: 98.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 100 mg/mL (271.36 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source