Brilaroxazine

Overview

Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A ( K i =1.5 nM) and 5-HT2A ( K i =2.5 nM), and has antagonist activity at 5-HT2B ( K i =0.19 nM), and 5-HT7 ( K i =2.7 nM) receptors. Brilaroxazine is an atypical antipsychotic agent, and has the potential to improve cognitive impairments in neuropsychiatric and neurological diseases in vivo.

Application

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Product Information

• Catalog No.: HY-109112
• CAS No.: 1239729-06-6
• Molecular Formula: C22H25Cl2N3O3
• Molecular Weight: 450.36
• Purity: 98.82%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.55 mM); Clear solution
• Availability: In-stock

Source

Original product source