MK-0752

Overview

MK-0752 is a potent, orally active and specific γ-secretase inhibitor, showing dose-dependent reduction of Aβ40 with an IC 50 of 5 nM in human SH-SY5Y cells. MK-0752 crosses the blood-brain barrier. MK-0752 reduces newly generated CNS Aβ in vivo.

Application

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Product Information

• Catalog No.: HY-10974
• CAS No.: 471905-41-6
• Molecular Formula: C21H21ClF2O4S
• Molecular Weight: 442.90
• Purity: 99.02%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.64 mM); Clear solution
• Availability: In-stock

Source

Original product source