N-Arachidonyldopamine

CAS No.：199875-69-9
Grade：98.36%
Formula：C28H41NO3
M.W.：439.63
Solvent：≥ 2.5 mg/mL (5.69 mM); Clear solution

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

N-Arachidonyldopamine acts as an Anandamide ( HY-10863 ) membrane transport inhibitor, a selective CB 1 cannabinoid receptor agonist, and a VR1 receptor activator. It exhibits an EC 50 value of 48 nM for rat VR1 and a K i value of 0.25 μM for CB1 . N-Arachidonyldopamine exists in mammalian neural tissues. It stimulates intracellular Ca 2+ mobilization, mediates cannabinoid-like effects, and induces hypothermia, hypomotility, catalepsy, analgesia, and hyperalgesia to heat. N-Arachidonyldopamine possesses anticancer activity against breast cancer . It can be used in research related to breast cancer and heat hyperalgesia.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Cannabinoid Receptor | Products > Signaling Pathways > TRP Channel | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Endogenous Metabolite

Product Information

Catalog No.: HY-110018
CAS No.: 199875-69-9
Molecular Formula: C28H41NO3
Molecular Weight: 439.63
Purity: 98.36%
Storage: Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Solubility: ≥ 2.5 mg/mL (5.69 mM); Clear solution
Availability: In-stock

Source

Original product source

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