GW1929 hydrochloride is an orally active peroxisome proliferator-activated receptor-γ ( PPARγ ) agonist with a pK i of 8.84 for human PPAR-γ , and pEC 50 s of 8.56 and 8.27 for human PPAR-γ and murine PPAR-γ , respectively. GW1929 hydrochloride has antidiabetic efficacy and neuroprotective potential. GW1929 hydrochloride suppresses neuronal apoptosis and shows anti-inflammatory potential.
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