(±)-NBI-74330

Overview

(±)-NBI-74330 is a potent and selective CXCR3 antagonist. (±)-NBI-74330 not only reduces tactile and thermal hypersensitivity but also enhances the analgesic properties of morphine. (±)-NBI-74330 can reduce microglial cell activation, increase astroglial cell activation, and downregulate the expression of some CXCR3 ligands in a rat neuropathic pain model.

Application

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Product Information

• Catalog No.: HY-110099
• CAS No.: 473722-68-8
• Molecular Formula: C32H27F4N5O3
• Molecular Weight: 605.58
• Purity: 99.12%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.13 mM); Clear solution
• Availability: In-stock

Source

Original product source