SM-324405

Overview

SM-324405 is a TLR7 agonistic antedrug ( EC 50 = 50 nM), with pEC 50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7 , respectively. SM-324405 is used for immunoresearch of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Pain | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR)

Product Information

• Catalog No.: HY-110207
• CAS No.: 677773-91-0
• Molecular Formula: C19H23N5O4
• Molecular Weight: 385.42
• Purity: 98.52%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.49 mM); Clear solution
• Availability: In-stock

Source

Original product source