GN44028

Overview

GN44028 is a potent and orally active hypoxia inducible factor ( HIF )-1α inhibitor, with an IC 50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers.

Application

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Product Information

• Catalog No.: HY-110266
• CAS No.: 1421448-26-1
• Molecular Formula: C18H15N3O2
• Molecular Weight: 305.33
• Purity: 99.60%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.19 mM); Clear solution
• Availability: In-stock

Source

Original product source