QAQ dichloride

Overview

QAQ dichloride, a photoswitchable voltage-gated Na v and K v channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-110358
• CAS No.: 1204416-85-2
• Molecular Formula: C28H44Cl2N6O2
• Molecular Weight: 567.59
• Purity: 98.68%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1 mg/mL (1.76 mM); Clear solution
• Availability: In-stock

Source

Original product source