ONO-2952

Overview

ONO-2952 is a potent, selective and orally active translocator protein 18 kDa (TSPO) antagonist with K i of 0.33-9.30 nM for rat and human TSPO . ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes . ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain without the amnesic effect. ONO-2952 has the potential for irritable bowel syndrome treatment.

Application

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Product Information

• Catalog No.: HY-111191
• CAS No.: 895169-20-7
• Molecular Formula: C22H20ClFN2O2
• Molecular Weight: 398.86
• Purity: 99.51%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 4.5 mg/mL (11.28 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source