ABT-384

Overview

ABT-384 is a potent, selective 11-β-hydroxysteroid dehydrogenase type 1 ( 11β-HSD1 ) inhibitor. ABT-384 exhibits high affinity ( K i 0.1-2.7 nM) against rodent, monkey, and human 11β-HSD1. ABT-384 blocks regeneration of active cortisol. ABT-384 can be used for the research of Alzheimer’s disease (AD).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Obesity | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > 11β-HSD

Product Information

• Catalog No.: HY-111262
• CAS No.: 868623-40-9
• Molecular Formula: C25H34F3N5O2
• Molecular Weight: 493.56
• Purity: 99.85%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution
• Availability: In-stock

Source

Original product source