ICI 169369 free base

Overview

ICI 169369 (free base) is an orally active, selective and non-competitive antagonist against 5HT receptor . ICI 169369 (free base) blunts the vasopressin (AVP), but not the ACTH, prolactin or growth hormone reponses to insulin-induced hypoglycaemia. ICI 169369 (free base) blocks centrally mediated 5-HT responses and lowers portal pressure in portal hypertensive rats.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-111291
• CAS No.: 85273-95-6
• Molecular Formula: C19H20N2S
• Molecular Weight: 308.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source