ML351

Overview

ML351 is a potent and highly specific 15-LOX-1 inhibitor with an IC 50 of 200 nM. ML351 shows excellent selectivity (>250-fold) versus the related isozymes, 5-LOX , platelet 12-LOX , 15-LOX-2, ovine COX-1 , and human COX-2 . ML351 prevents dysglycemia and reduces β-cell oxidative stress in nonobese diabetic mouse model of T1D.

Application

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Product Information

• Catalog No.: HY-111310
• CAS No.: 847163-28-4
• Molecular Formula: C15H11N3O
• Molecular Weight: 249.27
• Purity: 99.16%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (8.34 mM); Clear solution
• Availability: In-stock

Source

Original product source