Tacrine

Overview

Tacrine is an effective oral acetylcholine ( AChE ) inhibitor ( IC 50 = 109 nM) and also acts as an active substrate for CYP1A2 . Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-111338
• CAS No.: 321-64-2
• Molecular Formula: C13H14N2
• Molecular Weight: 198.27
• Purity: 99.10%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (12.61 mM); Clear solution
• Availability: In-stock

Source

Original product source