MS2734

Overview

MS2734 is a dual-substrate NNMT inhibitor that acts as a SAM ( HY-B0617 ) competitor and a non-competitor of Nicotinamide ( HY-B0150 ), with an IC 50 of 14 μM and a K d of 2.7 μM against hNNMT. MS2734 inhibits the methyltransferase activities of DOT1L ( IC 50 1.3 μM), PRMT7 ( IC 50 20 μM), BCDIN3D ( IC 50 40 μM) and SMYD2 ( IC 50 62 μM). MS2734 is applicable to research related to diabetes, obesity and various cancers.

Application

Products | Products > Disease Areas > Obesity | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Amine N-methyltransferase | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-111367
• CAS No.: 2587612-25-5
• Molecular Formula: C24H32N8O6
• Molecular Weight: 528.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source