UNC9994 hydrochloride

Overview

UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D 2 receptor ( D 2 R ) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a K i of 79 nM for D 2 R . UNC9994 hydrochloride is also an antagonist of G i -regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity.

Application

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Product Information

• Catalog No.: HY-111385
• CAS No.: 2108826-33-9
• Molecular Formula: C21H23Cl3N2OS
• Molecular Weight: 457.84
• Purity: 99.50%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (5.46 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source