NVS-SM2

Overview

NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC 50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-111520
• CAS No.: 1562333-92-9
• Molecular Formula: C23H30N6O
• Molecular Weight: 406.52
• Purity: 99.15%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source