Bragsin1

Bragsin1
  • CAS No.:369631-68-5
  • Grade:99.91%
  • Formula:C11H6F3NO4
  • M.W.:273.16
  • Solvent:≥ 2.08 mg/mL (7.61 mM); Clear solution

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2 , inhibits Arf GTPase activation, with an IC 50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Arf Family GTPase

Product Information

  • Catalog No.: HY-111549
  • CAS No.: 369631-68-5
  • Molecular Formula: C11H6F3NO4
  • Molecular Weight: 273.16
  • Purity: 99.91%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.08 mg/mL (7.61 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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