BAY-545 is a potent and selective A 2B adenosine receptor antagonist, with an IC 50 of 59 nM. BAY-545 also exhibits IC 50 s of 66, 400, 280 nM for human, mouse, rat A 2B adenosine receptor in cells, respectively, and a K i of 97 nM for human A 2B adenosine receptor , with more selectivity over A 1 , A 2A , and A 3 adenosine receptor .
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