ACY-1083

ACY-1083
  • CAS No.:1708113-43-2
  • Grade:99.54%
  • Formula:C17H18F2N4O2
  • M.W.:348.35
  • Solvent:≥ 5 mg/mL (14.35 mM); Clear solution

Overview

ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC 50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy.

Application

Products | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HDAC

Product Information

  • Catalog No.: HY-111791
  • CAS No.: 1708113-43-2
  • Molecular Formula: C17H18F2N4O2
  • Molecular Weight: 348.35
  • Purity: 99.54%
  • Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
  • Solubility: ≥ 5 mg/mL (14.35 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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