GSK1795091

CAS No.：1233589-81-5
Grade：94.48%
Formula：C81H157N2O16P
M.W.：1446.09
Solvent：≥ 2.5 mg/mL (1.73 mM); Clear solution

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

GSK1795091 (CRX-601), an immunologic stimulator, is a synthetic TLR4 agonist. Antitumor activity. GSK1795091 can be used as a vaccine adjuvant to enhance both mucosal and systemic immunity to influenza virus vaccines. Not only, GSK1795091 inhibits tumor growth and increases the survival in mice model, but results in long term survival in influenza challenge model in mice.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Toll-like Receptor (TLR)

Product Information

Catalog No.: HY-111792
CAS No.: 1233589-81-5
Molecular Formula: C81H157N2O16P
Molecular Weight: 1446.09
Purity: 94.48%
Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Solubility: ≥ 2.5 mg/mL (1.73 mM); Clear solution
Availability: In-stock

Source

Original product source

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