AZ31

Overview

AZ31 is a a potent, highly selective, and orally active ATM inhibitor with an IC 50 of <1.2 nM for ATM enzyme, and an IC 50 of 46 nM for ATM in cell. AZ31 shows excellent selectivity over ATR (>500-fold) and excellent PIKK-family selectivity and pan-kinase selectivity. AZ31 is a potent radiosensitizer in vitro, it can be used for the research of cancer .

Application

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Product Information

• Catalog No.: HY-112198
• CAS No.: 2088113-98-6
• Molecular Formula: C24H28N4O3
• Molecular Weight: 420.50
• Purity: 98.00%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source