CD532 hydrochloride

Overview

CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC 50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 hydrochloride also can directly interact with AURKA and induces a global conformational shift. CD532 hydrochloride can be used for the research of cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Aurora Kinase

Product Information

• Catalog No.: HY-112273A
• CAS No.: 2926498-81-7
• Molecular Formula: C26H26ClF3N8O
• Molecular Weight: 558.99
• Purity: 99.62%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (4.47 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source