CE-245677

Overview

CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC 50 s of 4.7 and 1 nM.

Application

Products | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Pain | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > Tie

Product Information

• Catalog No.: HY-112423
• CAS No.: 717899-97-3
• Molecular Formula: C24H22Cl2N6O3
• Molecular Weight: 513.38
• Purity: 98.00%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.05 mM); Clear solution
• Availability: In-stock

Source

Original product source