Chk2-IN-1

Overview

Chk2-IN-1 (compound 1) is a potent and selective inhibitor of checkpoint kinase 2 (Chk2) , with IC 50 s of 13.5 nM and 220.4 nM for Chk2 and Chk1 , respectively. Chk2-IN-1 can elicit a strong ataxia telangiectasia mutated ( ATM )-dependent Chk2-mediated radioprotection effect.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Checkpoint Kinase (Chk) | Products > Signaling Pathways > Choline Kinase

Product Information

• Catalog No.: HY-112477
• CAS No.: 724708-21-8
• Molecular Formula: C15H13N5O2
• Molecular Weight: 295.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source