(E/Z)-Chk2-IN-1

Overview

(E/Z)-Chk2-IN-1 ((E/Z)-Hymenialdisine analogue-1) (Compound 1) is a potent and selective cell cycle kinase Chk2 inhibitor with an IC 50 of 8 nM. (E/Z)-Chk2-IN-1 exhibits low inhibitory activity against other kinases (such as CK1δ , MEK1 , and PKCα/βⅡ ) with IC 50 values both >89 nM. (E/Z)-Chk2-IN-1 can be used for the research of cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PKC | Products > Signaling Pathways > Checkpoint Kinase (Chk) | Products > Signaling Pathways > Casein Kinase | Products > Signaling Pathways > MEK

Product Information

• Catalog No.: HY-112477A
• CAS No.: 693222-51-4
• Molecular Formula: C15H13N5O2
• Molecular Weight: 295.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source