IDH1 Inhibitor 1

Overview

IDH1 Inhibitor 1 is a potent, orally bioavailable, brain-penetrant and selective mutant IDH1 inhibitor with IC 50 s of 0.021 μM, 0.045 μM, and 2.52 μM for IDH1 R132H , IDH1 R132C , and IDH1 WT , respectively. Anticancer activity.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Isocitrate Dehydrogenase (IDH)

Product Information

• Catalog No.: HY-112601
• CAS No.: 2234285-81-3
• Molecular Formula: C20H18F4N6O2
• Molecular Weight: 450.39
• Purity: 99.96%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (5.55 mM); Clear solution
• Availability: In-stock

Source

Original product source