SGC-iMLLT

Overview

SGC-iMLLT is a first-in-class chemical probe and a potent, selective inhibitor of MLLT1/3-histone interactions with an IC 50 of 0.26 μM. SGC-iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9/YEATS3) with K d s of 0.129 and 0.077 μM, respectively.

Application

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Product Information

• Catalog No.: HY-112804
• CAS No.: 2255338-25-9
• Molecular Formula: C22H24N6O
• Molecular Weight: 388.47
• Purity: 99.33%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.35 mM); Clear solution
• Availability: In-stock

Source

Original product source