MA242

Overview

MA242 is a specific dual inhibitor of MDM2 and NFAT1 . MA242 directly binds both MDM2 and NFAT1 with high affinity, induces their protein degradation, and inhibits NFAT1-mediated transcription of MDM2 . MA242 induces apoptosis in pancreatic cancer cell lines regardless of p53 status.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-112816
• CAS No.: 1049704-18-8
• Molecular Formula: C26H21ClF3N3O5S
• Molecular Weight: 579.98
• Purity: 99.37%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (4.31 mM); Clear solution
• Availability: In-stock

Source

Original product source