Amg-1 is a potent, reversible and selective indoleamine 2,3-dioxygenase ( IDO1 ) inhibitor ( IC 50 = 3.0 μM). Amg-1 exhibits >80-fold selectivity over IDO2 ( IC 50 > 250 μM) and >20-fold selective over TDO ( IC 50 > 62.5 μM). Amg-1 can be used for cancer , hypotension, and neurological disorders research.
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