Guanosine 5'-diphosphate disodium salt

Overview

Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K + channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin ( HY-P70400 )- ferroportin interaction and modulates the interleukin-6 ( IL-6 )/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI).

Application

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Product Information

• Catalog No.: HY-113066A
• CAS No.: 7415-69-2
• Molecular Formula: C10H13N5Na2O11P2
• Molecular Weight: 487.16
• Purity: 96.42%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 100 mg/mL (205.27 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source