7-Ketocholesterol

Overview

7-Ketocholesterol is an oxidation product of cholesterol , widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol . 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase . 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis ( apoptosis ).

Application

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Product Information

• Catalog No.: HY-113342
• CAS No.: 566-28-9
• Molecular Formula: C27H44O2
• Molecular Weight: 400.64
• Purity: 99.87%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 0.62 mg/mL (1.55 mM); Clear solution
• Availability: In-stock

Source

Original product source