CUR61414

Overview

CUR61414 is a novel, potent and cell permeable Hedgehog signaling pathway inhibitor ( IC 50 =100-200 nM). CUR61414 is a small-molecule aminoproline class compound and selectively binds to smoothened ( Smo ) with a K i value of 44 nM. CUR-61414 can induce apoptosis in cancer cells without affecting neighboring non-tumor cells.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Gastric Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Hedgehog | Products > Signaling Pathways > Smo | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-113965
• CAS No.: 334998-36-6
• Molecular Formula: C31H42N4O5
• Molecular Weight: 550.69
• Purity: 99.04%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source