PLX5622

Overview

PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor ( IC 50 =0.016 μM; K i =5.9 nM). PLX5622 allows for extended and specific microglial cells elimination , preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals . PLX5622 is predominantly administered via ad libitum diets with a dose of 1200 ppm.

Application

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Product Information

• Catalog No.: HY-114153
• CAS No.: 1303420-67-8
• Molecular Formula: C21H19F2N5O
• Molecular Weight: 395.41
• Purity: 99.79%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 6.5 mg/mL (16.44 mM); Suspended solution; Need ultrasonic and warming
• Availability: In-stock

Source

Original product source