Octyl-α-ketoglutarate

Overview

Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase ( PHD ) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD .

Application

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Product Information

• Catalog No.: HY-114333
• CAS No.: 876150-14-0
• Molecular Formula: C13H22O5
• Molecular Weight: 258.31
• Purity: 99.9%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source