DS-1205b free base

Overview

DS-1205b free base is a potent and selective inhibitor of AXL kinase , with an IC 50 of 1.3 nM. DS-1205b free base also inhibits MER , MET , and TRKA , with IC 50 s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.

Application

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Product Information

• Catalog No.: HY-114357A
• CAS No.: 1855860-24-0
• Molecular Formula: C41H42FN5O7
• Molecular Weight: 735.80
• Purity: 99.92%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (3.40 mM); Clear solution
• Availability: In-stock

Source

Original product source