ST-539 is the inhibitor for deubiquitinase USP30 with IC 50 of 0.37 μM. ST-539 promotes the ubiquitination of mitochondrial proteins, and induces mitochondrial autophagy , thereby regulating mitochondrial homeostasis. ST-539 can be used in research of neurodegenerative diseases.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > Autophagy
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