MRTX-1257

Overview

MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC 50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.

Application

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Product Information

• Catalog No.: HY-114436
• CAS No.: 2206736-04-9
• Molecular Formula: C33H39N7O2
• Molecular Weight: 565.71
• Purity: 99.71%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (4.42 mM); Clear solution
• Availability: In-stock

Source

Original product source