BPHA is a potent and orally active MMP-2 , MMP-9 and MMP-14 inhibitor with IC 50 s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1 , -3, and -7 (the IC 50 s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP
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