ML404

Overview

ML404 (Compound 38) is an inhibitor of the mitochondrial permeability transition pore ( mtPTP ), which can suppress mitochondrial swelling ( EC 50 =4.9 nM) and only disrupts mitochondrial coupling (an adverse effect) at concentrations > 100 μM. ML404 can be utilized in research related to multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), muscular dystrophies (MD), myocardial infarction, and stroke.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

• Catalog No.: HY-114898
• CAS No.: 1826026-00-9
• Molecular Formula: C17H13ClN2O3
• Molecular Weight: 328.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source