ARN14494

Overview

ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC 50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti- apoptosis , and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research .

Application

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Product Information

• Catalog No.: HY-115498
• CAS No.: 1037837-27-6
• Molecular Formula: C24H32N4O3
• Molecular Weight: 424.54
• Purity: 99.08%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.78 mM); Clear solution
• Availability: In-stock

Source

Original product source