PF-05105679

Overview

PF-05105679, a chemical probe, is an orally active and selective TRPM8 antagonist with an IC 50 of 103 nM. PF-05105679 has the potential for cold-related pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-115506
• CAS No.: 1398583-31-7
• Molecular Formula: C26H21FN2O3
• Molecular Weight: 428.45
• Purity: 99.88%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.85 mM); Clear solution
• Availability: In-stock

Source

Original product source