GW280264X

Overview

GW280264X is the mixed ADAM10/TACE ( ADAM17 ) metalloproteinases inhibitor. GW280264X potently blocks TACE ( ADAM17 ) and ADAM10 with IC 50 s of 8.0 nM and 11.5 nM, respectively. ADAM10 and 17 modulate the immunogenicity of glioblastoma-initiating cells.

Application

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Product Information

• Catalog No.: HY-115670
• CAS No.: 866924-39-2
• Molecular Formula: C28H41N5O6S
• Molecular Weight: 575.72
• Purity: 99.30%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.61 mM); Clear solution
• Availability: In-stock

Source

Original product source