LQFM030

Overview

LQFM030 is a novel small molecule MDM2 inhibitor. LQFM030 exhibits concentration dependent cytotoxicity in K562 cells ( IC 50 = 0.28 mM). LQFM030 induces cell apoptosis through G0/G1 phase cell cycle arrest and increased Caspase activity. LQFM030 downregulates the mRNA expression of MDM2 , MDMX, p73, MYC , and NF-κB . LQFM030 is commonly used in research on cancers such as leukemia.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > c-Myc | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-115797
• CAS No.: 2180931-49-9
• Molecular Formula: C16H19ClN4O
• Molecular Weight: 318.80
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source