Benzo[c][1,8]naphthyridin-6(5H)-one

Overview

Benzo[c][1,8]naphthyridin-6(5H)-one exhibits low micromolar affinity to human adenosine receptor ( AR ) A 1 and hA 2A , with K i of 4.6 and 4.8 μM. Benzo[c][1,8]naphthyridin-6(5H)-one is inhibitor for poly ADP-ribose polymerase-1 ( PARP-1 ) and aurora kinase A, with IC 50 of 0.311 and 5.5 μM.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Adenosine Receptor | Products > Signaling Pathways > PARP | Products > Signaling Pathways > Aurora Kinase

Product Information

• Catalog No.: HY-115862
• CAS No.: 53439-81-9
• Molecular Formula: C12H8N2O
• Molecular Weight: 196.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source