GRPR antagonist-1

Overview

GRPR antagonist-1 is a potent gastrin releasing peptide receptor ( GRPR ) antagonist, having the cytotoxicity against certain cancer cells ( IC 50 of 4.97, 4.36 and 3.40 μM in PC3, Pan02 and HGC-27 cells, respectively). GRPR antagonist-1 inhibits HGC-27 cell viability by decreasing the Bcl-2 level and increasing the Bax level, causing apoptosis , with anticancer activity.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bombesin Receptor

Product Information

• Catalog No.: HY-115974
• CAS No.: 3052544-28-9
• Molecular Formula: C29H33F3N4O4
• Molecular Weight: 558.59
• Purity: 99.80%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution
• Availability: In-stock

Source

Original product source