(Rac)-Calpain Inhibitor XII

Overview

(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, K i =19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, K i =120 nM) and cathepsin B (K i =750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling , and cardiac response to injury.

Application

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Product Information

• Catalog No.: HY-116171
• CAS No.: 181769-57-3
• Molecular Formula: C26H34N4O5
• Molecular Weight: 482.57
• Purity: 99.04%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source